Basic Drugs in Urine - On-Line Analysis with TOX.I.S.™
Reagent Kit, Order Number: 60000

 

This ClinRep® Complete Kit is intended for use with the TOX.I.S.™ System from Shimadzu, an on-line HPLC system, which has been designed for automated drug screening (on-line analysis).

The analytical method allows for the reliable screening of more than 300 illegal basic* drugs, such as morphine, methadone, and amphetamine.

*For the drug screening of benzodiazepines, a group of acidic, neutral, and weak basic substances, an additional reagent kit is available (order no. 60100).

 
  • Reagent kit for the TOX.I.S™ system from Shimadzu

  • Identification of more than 300 alkaline drugs
 

Shimadzu TOX.I.S.™ / ClinRep® Reagent Kit

RECIPE and Shimadzu are offering a complete solution for the screening of illegal drugs in urine.

The TOX.I.S.™ system from Shimadzu is an on-line HPLC-system with photodiode array detection. It has been designed for the qualitative (and semiquantitative) screening on acute poisoning, drug abuse and doping.

The RECIPE reagent kit ensures a reliable and standardised HPLC analysis with Shimadzu’s TOX.I.S.™ system and contains buffers, an internal standard, and a test solution. Also, columns and accessories are provided.

The analytical method from Shimadzu allows for an automated sample extraction of more than 300 alkaline drugs of abuse, such as morphin, methadone, and amphetamine. The analyte identification bases on the comparison of retention times and on the comparison with the data of UV spectra libraries. For this purpose, the evaluation software of the system provides an appropriate UV spectra library. Additional compounds can be identified using a spectra library of toxicological relevant substances with approx. 3000 records.

 

Shimadzu TOX.I.S.™

 

Chromatogram of the ClinTest® Test Solution

Shimadzu TOX.I.S.   Chromatogram
    MDA: 21.33 min, Amphetamine: 21.82 min, 6-Acetylmorphine: 23.64 min, Methadone: 24.87 min, Morphine: 26.27 min, Tilidine: 27.88 min, Codeine: 31.81 min, EDDP: 35.45 min, Internal Standard: 40.09 min
     

 

Basic Drugs in Urine - On-Line Analysis with TOX.I.S.™
Reagent Kit, Order Number: 60000

Ordering Information

Order No. Description Quantity
60000   ClinRep® Reagent Kitfor the TOX.I.S.™ System of Shimadzu for 100 assays 1 pce.  
 
  Components of the reagent kit (order no. 60000):  
60007 Mobile Phase A 1700 ml
within the kit: 2 x order no. 60007
60008 Mobile Phase B 2000 ml
within the kit: 3 x order no. 60008
60009 SPE-Buffer 2500 ml
60012 IS Internal Standard 50 ml
60014 Test Solution 15 ml
within the kit: 2 x order no. 60014
60021 SPE-Washing Solution 1700 ml
within the kit: 2 x order no. 60021
 
  Additional Components:  
60006 Mobile Phase AB 2500 ml
     
  Start Accessories:  
60030 Analytical column with test chromatogram 1 pce.
60031 SPE-Column Holder incl. 1 SPE-Column 1 pce.
60032 SPE-Column 1 pce.
60033 Guard Column Holder incl. 1 Guard Column 1 pce.
60034 Guard Columns 10 pcs.
FK5820 Stainless steel prefilter holder 1 pce.
FK5821 Replacement filter for stainless steel prefilter holder 10 pcs.