This ClinMass® Complete Kit is an advancement of our reliable complete kit (order no. MS1000) for the therapeutic drug monitoring of cyclosporine A, tacrolimus, sirolimus and everolimus. The sample analysis is performed on-line within a 2 min injection interval.
For analysis a new internal standard containing the isotope labelled analytes (d12-Cyclosporin A, 13Cd2-Tacrolimus, 13Cd3-Sirolimus und 13C2d4-Everolimus) is available. For the optimisation of the tandem mass spectrometer and for the test run of the analytical system ClinMass® Optimisation Mixes are available. A 4-Level and a 7-Level ClinCal® Whole Blood Calibrator Set are provided for precise calibration and measurement. The calibration range may be optionally extended by use of an additional high calibration point. Quality control is performed with ClinChek® Whole Blood controls in five different levels (see ordering information).
The sample pretreatment can also be performed automated with Liquid Handling Systems and 96-well plates (see ClinMass® Complete Kit with order no. MS1200).